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A scientific review published in the National Library of Medicine in 2022 found that nose-to-brain delivery of therapeutic peptides is a non-invasive and fast-acting method that can effectively bypass the blood-brain barrier while minimizing systemic exposure

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Additionally, the peptide was also found to possess powerful cell-protective actions, such as anti-cancer activities and anti-inflammatory actions mediated through improved fibroblast activity and suppression of damaging inflammatory molecule production

discovered that inhibition of VEGF-B signaling reduced lipid accumulation in the kidney, mitigated renal lipotoxicity, and prevented renal dysfunction [117]